As the Revolutionary War draws to an end, the violence on the frontier only accelerates. The infamous Girty brothers incite Indians to a number of massacres, but when the Village of Peace, a Christian utopian settlement, is destroyed, the settlers know they will have to hunt Chief Wingenund down.
Lewis Wetzel, known to the Indians as the Death Wind, undertakes this mission of revenge. The stakes increase when he learns of a planned attack on Fort Henry. Armed with only his long rifle and knife, Wetzel sets out to single-handedly turn the tide in this bloody border war.