Becoming a stand up comedian requires an understanding that performing stand up comedy can be stressful, particularly if you have hecklers. Some people enjoy going to the comedy clubs just to mess with the stand up comedians. They have created a technique for getting under your skin. When this happens, remain in control and do not make it personal. This may be very difficult at first, but if you let them get to you your show can spiral out of control.
Where stand up comedy writing is concerned, the more honest and vulnerable you are in your comedy shows, the more the audience will connect with you. Letting what you know and feel take control of your stand up comedy writing will open many more paths for you to find your jokes.